A unique approach for discovering new autophagy therapeutics

We also screen these new molecules in a variety of translatable cellular models of disease.

With Lysoseeker™ we have discovered several highly promising lead molecules which are being optimised towards the clinic and restore autophagy in vivo via completely novel biology.

The process of autophagy features multiple steps and is highly dynamic.

We are building an understanding of these processes at a transcriptional and proteomic level and probing them with molecules to discover new intervention points, with the goal of boosting the whole process.

Our unbiased approach is leading to numerous opportunities for intervention.