A selection of recent
publications from the
Samsara team

Publications

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms (2021) Journal for Immunotherapy of Cancer

Digesting the crisis: autophagy and coronaviruses (2020) Microbial Cell

Importance of Quantifying Drug-Target Engagement in Cells (2020) ACS Med. Chem. Lett.

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects (2020) Autophagy

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential (2019) Cell Metabolism

Biological Functions of Autophagy Genes: A Disease Perspective (2019)

Yeast as a tool to identify anti-aging compounds (2018) Oxford Journals: FEMS Yeast Research

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species (2018) Nature Communications

Therapeutic modulation of autophagy: Which disease comes first? (2019) Cell Death & Differentiation

The Hallmarks of Aging (2013) Cell

The Lysoseeker™ Platform

A unique approach for discovering new autophagy therapeutics.

Rare Monogenic Disease

What if we could offer real hope for serious rare genetic diseases?

Neurodegeneration

What if we could tackle the cause of Alzheimer’s and Parkinson’s Disease?

Our Pipeline

Samsara is leveraging its knowledge of new autophagy biology.

Autophagy, healthspan and lifespan

Autophagy, healthspan and lifespan

Our strategy in Samsara is to treat diseases where there is a high unmet need. But we also want to find out how our molecules work to affect healthspan and longevity.

Introducing Samsara

Introducing Samsara

Over the last twenty years or so, the phenomenon of autophagy has become a hot topic in the world of biology.

© 2021 Samsara Therapeutics | Legal Information | Privacy

© 2021 Samsara Therapeutics
Legal Information | Privacy