We are discovering new therapeutics for cellular rejuvenation

This is a new frontier of biology

What if we could discover new therapeutics that remove toxic proteins from your cell, boost your immune system and replenish your cell’s energy stores?

Autophagy is a process of cellular renewal which occurs in all the cells of the body. Its role is to clear unwanted proteins, organelles and even invading bodies such as viruses and bacteria, cutting them up into building blocks which can be used by the cell to make new proteins.

Autophagy occurs at a low level continuously but is boosted when we exercise or when we are hungry. And many studies have shown that boosting autophagy in model organisms significantly extends lifespan.

When we age, the ability of our cells to undergo autophagy reduces. And in many diseases, particularly ones which have a genetic basis, we see dysfunctional autophagy. In fact there is huge and compelling evidence from human genetics that many diseases are driven by autophagy dysfunction.

Samsara’s mission is to discover new mechanisms which can restore autophagy, and at the same time new drugs which use these mechanisms for the treatment of genetically defined diseases.

Our people

Samsara has been created by Apollo Health Ventures and features an experienced leadership team that pairs vast experience in pharma, biotech and the science of aging, and a highly skilled scientific team based in our new labs in Oxford.

Our scientific co-founders Professor Guido Kroemer and Professor Frank Madeo are world leaders in the fields of geroscience and cellular homeostasis.



Jens Eckstein, PhD


Peter Hamley, PhD, MBA

Chief Scientific Officer

Warren Galloway, PhD

Head of Chemistry

John Blackwood

John K. Blackwood, PhD

Head of Biology

Scientific Team

Alkmini Kalousi, PhD

Nancy Malintan, PhD

Sergio Rotondo, PhD

Jakub Stefaniak, PhD

Scientific Advisors

Prof. Guido Kroemer

Scientific Founder

Prof. Frank Madeo

Scientific Founder

Prof. Didac Carmona-Gutierrez

Scientific Founder

Prof. Oliver Kepp

Scientific Founder

Sebastian A. Brunemeier

EIR & Advisor

We have major collaborations with INSERM and the University of Graz which fuel our platform, and we have established a cutting edge new laboratory in Oxford

© 2021 Samsara Therapeutics | Legal Information | Privacy

© 2021 Samsara Therapeutics
Legal Information | Privacy